Position: Doctoral Researcher
Laboratoire Écologie, Systématique, Évolution
Bât. 360, rue du Doyen André Guinier
91405 Orsay Cedex
Email: marine.duhamel (at) u-psud.fr
I am a PhD student cosupervised by Tatiana Giraud (Université Paris-Saclay, France) and Dominik Begerow (Ruhr-Bochum Universität, Germany). I work on the adaptation of Microbotryum fungi, that are castrating plant pathogens. I study the genomic mechanisms of host adaptation in these fungi and the evolution of their mating-type chromosomes. Fungal plant pathogens are generally highly specialized on their host species. However, host shifts can occur and cause emerging diseases that are a major issue in agronomic systems. Therefore, it is essential to better understand the genomic basis of adaptation in fungal pathogens. In addition, the evolution of mating-type chromosomes is still poorly understood. I am particularly interested in the accumulation dynamics of transposable elements in non-recombining regions of mating-type chromosomes in these fungi and in their genome.
2018-2021: PhD at University Paris Saclay (France) and University of Ruhr (Germany) under the supervision of Tatiana Giraud and Dominik Begerow. Genomic mechanisms involved in host specialization in Microbotryum fungi.
2016-2018: Master Degree in Bioinformatics at University Paris Sud, France
2014-2016 : Master Degree in Biology-Health specialty Plant Sciences at University Paris-Sud, France
2011-2014 : Bachelor in Organism Biology and Ecology at University Paris-Sud, France
2011 : Scientific Baccalaureate at Gustave Flaubert High School, Rouen, France
Kumar, R, Duhamel, M, Coutant, E, Ben-Nahia, E, Mercier, R (2019). Antagonism between BRCA2 and FIGL1 regulates homologous recombination. Nucleic Acids Res., 47, 10:5170-5180.
Fernandes, JB, Duhamel, M, Seguéla-Arnaud, M, Froger, N, Girard, C, Choinard, S, Solier, V, De Winne, N, De Jaeger, G, Gevaert, K, Andrey, P, Grelon, M, Guerois, R, Kumar, R, Mercier, R (2018). FIGL1 and its novel partner FLIP form a conserved complex that regulates homologous recombination. PLoS Genet., 14, 4:e1007317.